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Diphenhydramine overdose

Contents of this page:

Alternative Names   

Benadryl overdose; Sominex overdose; Nytol overdose

Definition    Return to top

This article discusses the health effects from an overdose of diphenhydramine, which is found in various over-the-counter allergy and sleep medicines.

Overdose occurs when someone accidentally or intentionally takes more than the normal or recommended amount of a drug or medication.

This is for information only and not for use in the treatment or management of an actual poison exposure. If you have an exposure, you should call your local emergency number (such as 911) or the National Poison Control Center at 1-800-222-1222.

Poisonous Ingredient    Return to top

Where Found    Return to top

The ingredient diphenhydramine may be found in the following products: This list is not all-inclusive.

Symptoms    Return to top

Before Calling Emergency    Return to top

Determine the following information:

However, DO NOT delay calling for help if this information is not immediately available.

Poison Control    Return to top

The National Poison Control Center (1-800-222-1222) can be called from anywhere in the United States. This national hotline number will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

See: Poison control center - emergency number

What to Expect at the Emergency Room    Return to top

The health care provider will measure and monitor the patient's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated as appropriate. The patient may receive:

Outlook (Prognosis)    Return to top

Recovery is very likely.

References    Return to top

Wax P. Anticholinergic Toxicity. In: Tintinalli J. et al. Emergency Medicine - A Comprehensive Study Guide. 6th ed. McGraw-Hill; 2004: chap 183.

Update Date: 2/5/2009

Updated by: A.D.A.M. Editorial Team: David Zieve, MD, MHA, Greg Juhn, MTPW, David R. Eltz. Previously reviewed by Stephen C Acosta, MD, Department of Emergency Medicine, Portland VA Medical Center, Portland, OR. Review provided by VeriMed Healthcare Network (10/30/2008).

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The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 1997-2009, A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.